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. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: J Exp Zool A Ecol Genet Physiol. 2009 Jun 1;311(5):346–357. doi: 10.1002/jez.451

TABLE 1.

Estimated 50% inhibitory concentrations (IC50: nM) for human 11β-hydroxylase and porcine gonadal aromatase (P450arom) cytochromes P450 for the compounds etomidate and fadrozole, presumed specific for P450c11 and P450arom, respectively. Data were taken from the sources indicated

Human P450c11 Porcine gonadal P450arom
etomidate 1–10 100
fadrozole 10–30 2