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. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: Laryngoscope. 2009 Jun;119(6):1153–1165. doi: 10.1002/lary.20157

Figure 5.

Figure 5

To determine if SU5402 was toxic to explant cultures, larynx-trachea explants were cultured in this FGF pathway inhibitor for 24 hours. The media was changed and the SU5402 removed, and the tissue cultured for another 24 hours. Removal of the SU5402 demonstrated a significant (p<0.05) increase in Sox9 expression (yellow) compared to control cultures in which the SU5402 was not removed (red). Sox9 expression in both SU5402 treated explant cultures was significantly decreased (p<0.05) compared to the DMSO control (blue).