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Gas phase structures for Aβ(21-30) mutants: Arctic E22G (a), Dutch E22Q (b) Italian E22K (c) and Iowa D23N (d). All structures are the central structure of cluster C1. The structure of the WT peptide is shown as a transparent image behind each mutant. For all the structures, the bend region at residues 23-28 is shown in gray and dotted lines denote key hydrogen bonds.
