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. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: Chem Biol. 2007 Dec;14(12):1323–1333. doi: 10.1016/j.chembiol.2007.10.016

Figure 4.

Figure 4

Endothelial cell proliferation and migration assays. (A) Y341A mutation activated full-length TyrRS for stimulating proliferation of bovine aortic endothelial cells. Cell proliferation was measured in five randomly chosen HPFs by the percentage of cells with positive bromodeoxyuridine (BrdU) incorporation. Samples were run in triplicate and mean ± s.d. is shown. (B) Y341A mutation activated full-length TyrRS for stimulating migration of human umbilical vein endothelial cells. Migration of untreated monolayers was normalized to 1. Data from eight experiments were collected for each sample and mean ± s.d. is shown.