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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Gastroenterology. 2009 Mar 18;136(7):2356–2364. doi: 10.1053/j.gastro.2009.03.003

Figure 7. Effects of naproxen on cytoprotective gene expression in CFSC-8B rat stellate cells cultured under normoxia and hypoxia conditions.

Figure 7

(A) Shows RT-PCR for cellular mRNAs indicating increases in expression of HGF and VEGF mRNAs with naproxen, up to 1 μM, especially under hypoxia conditions. (B) Shows VEGF protein levels in culture medium, which increased from 409±10 pg/ml and 424±5 pg/ml under basal normoxia and hypoxia conditions, respectively, to 648±26 pg/ml (1.8-fold) and 1133±42 pg/ml (2.8-fold) after culture with 1 μM naproxen under corresponding conditions, p<0.05, ANOVA.