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. Author manuscript; available in PMC: 2010 May 26.
Published in final edited form as: Curr Biol. 2009 Apr 16;19(10):848–852. doi: 10.1016/j.cub.2009.03.051

Figure 2.

Figure 2

An abrupt phase delay of the LD cycle, similar to jetlag, induces transient desynchrony of sleep stages in the rat. a: actograms representing the daily course of total sleep, REMS, delta power, CBT and locomotor activity of an animal exposed to an abrupt 6-h phase delay of its 12:12 LD cycle. Lights-OFF time was delayed by 6 h on day 0, followed by one 12:12 cycle of the new LD schedule (day 1) before release into constant darkness (day 2). White and gray areas represent the times of lights ON and OFF, respectively. b: The time course change of the acrophase of REM and delta power before and after the 6-h delay in the LD cycle (day 0). Points represent means + or − the standard error (n = 5). Blocks of days marked with different letters denote statistically significant differences (one-way ANOVA) in the acrophase difference between the two stages. c: An example of a spontaneous transition from wake to REMS in an animal that underwent a phase delay under the conditions shown in a. Representative EEG and EMG recordings are shown for each vigilance state; the wake-to-REMS transition (arrow) is shown in the bottom traces.