Table 1.
Gene clusters up-regulated by KLF4
| Symbol | Gene name | Symbol | Gene name |
|---|---|---|---|
| Metabolism | Structural | ||
| ALPI | Alkaline phosphatase, intestinal | KRT18 | Keratin 18 |
| ALPP | Alkaline phosphatase, placental | KRT13 | Keratin 13 |
| CTBS | Di-N-acetyl-chitobiase | VIL2 | Villin 2 (ezrin) |
| RDP | Dipeptidase 1, renal | MCM | Methylmalonyl coenzyme A mutase |
| PRODH | Proline dehydrogenase 1 | KRTHB1 | Keratin, hair, basic 1 |
| CAMK1 | Calmodulin-dep. protein kinase 1 | RTN2C | Reticulon 2C |
| AGPAT2 | 1-Acylglycerol-3-phosphate O-acyltransferase 2 | SNL | Singed-like (fascin homolog, sea urchin) |
| PON | Paraoxinase 1 | KRTHB3 | Keratin, hair, basic 3 |
| AAT | Antitrypsin serine (or cysteine) proteinase inhibitor, clade A (α-1 antiproteinase, antitrypsin), member 1 | KRT8 | Keratin 8 |
| ASS | Argininosuccinate synthetase | KRT2A | Keratin 2A |
| DHCR7 | 7-Dehydrocholesterol reductase | KRT6A | Keratin 6A |
| B4GALT1 | UDP-Gal: β GlcNAc β 1,4- galactosyltransferase 1 | KRT7 | Keratin 7 |
| GCNT3 | Glucosaminyl (N-acetyl) transferase 3, mucin-type | KRT15 | Keratin 15 |
| KLK1 | Kallikrein 1 | DSG2 | Desmoglein 2 |
| CSTB | Cystatin B (stefin B) | VIM | Vimentin |
| Cell cycle control | Signal transduction | ||
| p57/Kip2 | Cyclin-dependent kinase inhibitor 1C | MT1L | Metallothionein 1L |
| IGFBP6 | Insulin-like growth factor binding protein 6 | ADSF | Adipose specific 2 |
| p21/Cip1 | Cyclin-dependent kinase inhibitor 1A | GNAI2B | Guanine nucleotide binding protein, α inhibiting activity 2 |
| SFN | Stratifin (14-3-3 sigma) | GPRK5 | G protein-coupled receptor kinase 5 |
| PGGT1B | Protein geranyl-geranyltransferase type I β | CRIP2 | Cysteine-rich protein 2 |
| PPFIA3 | Protein tyrosine phosphatase, receptor type, f polypeptide, interacting protein, α 3 | MT1E | Metallothionein 1E |
| UFD2 | Ubiquitination factor E4B | EST | Highly similar to metallothionein-IB |
| Immune response | Translation | ||
| HBZ | Hemoglobin, zeta | TCEA2 | Transcription elongation factor A (SII), 2 |
| ENTPD2 | Ectonucleoside triphosphate diphosphohydrolase 2 | RNA helicase | RNA helicase-related protein |
| HCG II | H. sapiens HCG II mRNA | EST | Moderately similar to integrase |
| HBG1 | Hemoglobin, γA | ||
| ARHH | Ras homolog gene family, member H | Other | |
| FUT1 | Fucosyltransferase 1 | CDNA | cDNA FLJ13155, human |
| NK4 | Natural killer cell transcript 4 | CDNA | cDNA FLJ11658, human |
| PVRL1 | Poliovirus receptor-related 1 | CYP4F1-like | Rat CYP4F1-like |
| FTL | Ferritin, light polypeptide |