Figure 2.

Effects of atropine, L-NAME and D-Lys³-GHRP-6 on the gastroprokinetics of ghrelin or GHRP-6 in the DM mice. Mice were pretreated with atropine (1 mg/kg), L-NAME (50 mg/kg) or D-Lys³-GHRP-6 (5 μmol/kg) before administration of ghrelin (100 μg/kg) or GHRP-6 (100 μg/kg), and the effects were compared with those of treatment with ghrelin or GHRP-6 (100 μg/kg) alone. Bar graph and error bars represent the means ± SE of at least six animals. ^aP < 0.05 vs treatment with ghrelin or GHRP-6 (100 μg/kg) alone.