Table 6.
Probability ratios for the combinations of ADH1B, CYP2E1 and ALDH2 genotypes among moderate-to-heavy drinkers, n (%)
| Combined genotypes | Genotype | Cases (n = 80) | Controls (n = 480) | OR | 95% CI | |
| ALDH2 + ADH1B | ALDH2*1/1 +ADH1B*1/2 +2/2 | 28 (35.0) | 144 (30.0) | 1 | ||
| ALDH2*1/2 + | 15 (18.8) | 27 (1.9) | 7.46 | 3.28-18.32 | ||
| ADH1B*1/1 | ||||||
| ALDH2 + CYP2E1 | ALDH2*1/1 +CYP2E1*c1/c2 +c2/c2 | 10 (12.5) | 60 (12.5) | 1 | ||
| ALDH2*1/2 +CYP2E1*c1/c1 | 32 (40.0) | 15 (3.1) | 6.82 | 1.44-9.76 | ||
| ADH1B + CYP2E1 | ADH1B*1/2 +2/2 +CYP2E1*c1/c2 +c2/c2 | 12 (15.0) | 36 (2.5) | 1 | ||
| ADH1B*1/1 +CYP2E1*c1/c1 | 14 (17.5) | 66 (13.8) | 6 |