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Mean cortisol (A) and ACTH (B) concentrations monitored overnight. Data were segmented into 2-h windows and subjected to two-way ANOVA in a repeated-measures design. Different alphabetic letters denote significant contrasts among time segments independently of treatment (capital letters) and among PLAC, KTCZ, and METY treatments within any given time segment (lower-case letters). Data are the mean±S.E.M. (N = 6 subjects).
