Table 2.
rs1800795 genotypic and allelic frequencies according to age and sex. M Men, F women
| Age bracket (n) | Genotype count (%) | Allele count (%) | P–value | ||||
|---|---|---|---|---|---|---|---|
| G/G | G/C | C/C | G/C | C/C | |||
| Trelong study | |||||||
| 70–85 (309) | 159 (51.4) | 125(40.5) | 25(8.1) | 443 (71.7) | 175 (28.3) | ||
| M (158) | 79 (50.0) | 62 (39.2) | 17 (10.8) | 220 (69.6) | 96 (30.4) | ||
| F (151) | 80 (53.0) | 63 (41.7) | 8 (5.3) | 223 (73.8) | 79 (26.2) | ||
| 85+ (244) | 118 (48.4) | 114 (46.7) | 12 (4.9) | 350 (71.7) | 138 (28.3) | ||
| M (98) | 47 (48.0) | 49 (50.0) | 2 (2.0)* | 143 (73.0) | 53 (27.0) | P= 0.006* | |
| F (146) | 71 (48.7) | 65 (44.5) | 10 (6.8) | 207 (70.9) | 85 (29.1) | ||
| Milan study | |||||||
| 70–85 (98) | 51 (52.0) | 36 (36.7) | 11 (11.3) | 138 (70.4) | 58 (29.6) | ||
| M (38) | 19 (50.0) | 15 (39.5) | 4 (10.5) | 53 (69.7) | 23 (30.3) | ||
| F (60) | 32 (53.3) | 21 (35.0) | 7 (11.6) | 85 (70.8) | 35 (29.2) | ||
| 85+ (138) | 68 (49.3) | 56 (40.6) | 14 (10.1) | 192 (69.6) | 84 (30.4) | ||
| M (77) | 36 (46.7) | 36 (46.7) | 5 (6.6)* | 108 (70.1) | 46 (29.9) | P = 0.2* | |
| F (61) | 32(52.4) | 21(35.0) | 8 (12.6) | 85 (69.7) | 37 (30.3) | ||
| Total (M) | |||||||
| 70–85 (196) | 98 (50.0) | 77 (39.3) | 21(10.7) | 273 (69.6) | 119 (30.4) | ||
| 85+ (175) | 83 (47.4) | 85 (48.6) | 7(4.0)* | 251 (71.7) | 99 (28.3) | P = 0.04* | |
* vs M 70–85, χ2-test