Table 2.
The clinicopathological data of nonobese (BMI < 25 kg/m2) and obese (BMI ≥ 25 kg/m2) patients with recurrent hepatocellular carcinoma who underwent a repeat hepatectomy
| Variables | BMI < 25 kg/m2 (n = 44) | BMI ≥ 25 kg/m2 (n = 16) | P value |
| Age | 67.0 ± 10.3 | 67.7 ± 7.6 | 0.809 |
| Gender (male:female) | 32:12 | 7:9 | <0.05 |
| Body mass index (kg/m2) | 21.9 ± 2.0 | 26.9 ± 1.3 | <0.01 |
| Diabetes mellitus (%) | 24.4 | 20 | 0.728 |
| Positive HCV antibody (%) | 70.5 | 80 | 0.463 |
| Liver function data | |||
| AST (international units/L) | 39.7 ± 24.7 | 46.8 ± 31.0 | 0.367 |
| Albumin (g/dL) | 4.0 ± 0.5 | 3.9 ± 0.4 | 0.427 |
| Prothrombin time (%) | 87.7 ± 13.3 | 83.6 ± 17.7 | 0.352 |
| Child-Pugh class (A:B) | 43:01:00 | 14:02 | 0.136 |
| Operative data | |||
| Procedures (Hr0/HrS:Hr1/Hr2) | 40:4 | 16:0 | 0.108 |
| Operation time (min) | 188 ± 68 | 243 ± 100 | <0.05 |
| Blood loss (g) | 453 ± 336 | 1044 ± 1120 | <0.01 |
| Blood transfusion (%) | 6.8 | 25 | 0.068 |
| Postoperative complications (%) | 9.1 | 25 | 0.128 |
| Postoperative hospital death (%) | 0 | 0 | 0.999 |
| Tumor factors | |||
| Tumor size (cm) | 2.0 ± 0.8 | 2.4 ± 1.3 | 0.197 |
| Solitary tumor (%) | 72.3 | 81.3 | 0.491 |
| Positive fc (%) | 42.9 | 53.3 | 0.485 |
| Positive vp (%) | 42.9 | 53.3 | 0.307 |
| Positive im (%) | 11.9 | 0 | 0.073 |
| Well/Moderately/Poorly1 | 6/29/6 | 5/9/2 | 0.384 |
| AFP (> 20 ng/mL) (%) | 46.5 | 60 | 0.367 |
BMI: Body mass index; HCV: Hepatitis C virus; AST: Aspartate transaminase; Hr0: Resection less than subsegmentectomy; HrS: Subsegmentectomy; Hr1: Segmentectomy; Hr2: Bisegmentectomy; fc: Capsular formation; vp:Invasion to portal vein; im: intrahepatic metastasis; AFP: Alpha-fetoprotein.
1
Histologic differentiation of the tumor.