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. 2007 Oct 31;22(5):898–904. doi: 10.3346/jkms.2007.22.5.898

Fig. 1.

Fig. 1

The concentration of TGF-β1 to induce A549 cells to undergo EMT. A549 cells were incubated with TGF-β1 at various concentrations for 48 hr. (A) Morphologic changes are observed with 0.05 ng/mL of TGF-β1, and TGF-β1 treated cells with concentration as high as 5 ng/mL show more fibroblast-like morphologic changes. a, control; b, 0.05 ng/mL; c, 0.5 ng/mL; d, 5 ng/mL TGF-β1. (B) Expression of epithelial marker E-cadherin and cytokeratin are down-regulated by TGF-β1 stimulation in a concentration-dependent manner.