Table 4.
Arsenicals | Acute Toxicity | Chronic Toxicity | Comments |
---|---|---|---|
Orpiment | N/A | Negative in micronucleus assay | High As levels in blood |
Negative in lung tumor formation | |||
Reaglar | N/A | Cutaneous manifestations | Adverse effects |
Mild GI discomfort in chemotherapy | Tolerable | ||
Prolonged QT, dose-dependent | Tolerable | ||
Fatty liver, but no liver fibrosis | Long-term exposure | ||
Arsenic trioxide | Sudden death, poisoning | Cardiac effects and GI effects | Chelation effective |
Skin and GI effects | Tolerable | ||
No secondary cancer reports |