Figure 5. TSPO in astrocytes in HIVE.
All cases of HIVE displayed some degree of astrocytic expression. One case with relatively high astrocytic expression of the TSPO is shown with double-label IHC for GFAP (A, D panels). The same case is stained for TSPO with HIV-1 p24 (B). Two other cases with less astrocytic staining are shown (C, E panels). Note that GFAP+ astrocytes are not double-labeled in these cases. Double-labeled astrocytes are indicated with arrowheads, while TSPO-expressing microglia (GFAP−) are indicated with arrows. The scale bar represents 30 μm in A and C, 60 μm in B, 12.5 μm in D and 50 μm in E.