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. Author manuscript; available in PMC: 2009 Jun 8.
Published in final edited form as: Curr Med Chem. 2008;15(19):1863–1869. doi: 10.2174/092986708785132915

Table 1.

Signaling of EP receptor subtypes

EP1 EP2 EP3 EP4
PGE2 Kd (nM)/Human (Mouse) 9.1 (20) 4.9 (12) 0.3 (0.9) 0.8 (1.9)
G-protein Coupling Unknown (↑ Ca2+) Gs Gs, Gi, Gq Gs