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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Mol Cell Neurosci. 2008 Nov 1;40(2):167–186. doi: 10.1016/j.mcn.2008.10.003

Figure 2. EGFP labeling at E12.5 in I12b-Cre;Z/EG and URE2-Cre;Z/EG reveals strong forebrain expression.

Figure 2

(A-B) Immunohistochemistry for EGFP on parasagittal sections through an E12.5 (A) I12b-Cre;Z/EG or (B) URE2-Cre;Z/EG animal.

(C-D) Immunohistochemistry for EGFP on coronal sections through the E12.5 forebrain of (C) I12b-Cre;Z/EG or (D) URE2-Cre;Z/EG mice. EGFP expression is present in the CGE in I12b-Cre;Z/EG but not URE2-Cre;Z/EG. Also note that tangentially migrating cells (arrowhead) are readily detected in I12b-Cre;Z/EG forebrain.

cge, caudal ganglionic eminence; drg, dorsal root ganglion; ge, ganglionic eminences; hyp, hypothalamus; lge, lateral ganglionic eminence; mge, medial ganglionic eminence; ob, olfactory bulb; oe, olfactory epithelium; poa, preoptic area; pth, prethalamus; s, skin; svz, subventricular zones; v, trigeminal ganglion. Scale bar in A = 1mm and in C = 500 μm.