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. Author manuscript; available in PMC: 2009 Jun 9.
Published in final edited form as: Exp Mol Pathol. 2007 Apr 18;83(2):188–197. doi: 10.1016/j.yexmp.2007.03.008

Table 2.

Characteristics of human lymph node metastases.

Tissue Designation1 Tumor Type pTNM2 Stage2 Cystatin M Expression
P1N1 lymph node metastasis T2N1Mx IIB Yes
P2N1-N33 lymph node metastasis T1cN3aMx IIIC No
P3N1 lymph node metastasis T2N1Mx IIB Yes
P4N1 lymph node metastasis T2N1Mx IIB No
P5N1 lymph node metastasis T1cN2aMx IIA No
LNM1-44 lymph node metastasis TxNxMx UNK No
LNM5 lymph node metastasis TxNxMx UNK No
LNM6 lymph node metastasis T3N3aM0 IIIC Yes
LNM7 lymph node metastasis T3N3aM0 IIIC No
LNM8 lymph node metastasis T3N3aM0 IIIC No
LNM9 lymph node metastasis T3N3M0 IIIC No
LNM10 lymph node metastasis T3N2aM0 IIIA No
LNM11 lymph node metastasis T1cN1aM0 IIA No
LMN12 lymph node metastasis T2N3aM0 IIIC No
LMN13 lymph node metastasis T1bN3aM0 IIIC No
1

Metastaic lesions corresponding to a matched primary breast tumor are indicated as PxNx and lesions that have no matched primary are designated LNMx.

2

pTNM and pathological stage designations for lymph node metastases are derived from primary breast tumor designations. TxMxNx refers to a pTNM that is unknown.

3

P2N1-N3 designates 3 independent lymph nodes corresponding to one primary tumor.

4

LNM1-4 designates 4 independent lymph nodes corresponding to one primary tumor.