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. 2009 Mar 25;101(6):2995–3011. doi: 10.1152/jn.90740.2008

FIG. 6.

FIG. 6.

Entrainment of bursting is less reliable and locomotor-like activity is abolished in the presence of the mGluR1 antagonist 7-(hydroxyimino)cyclopropa[β]chromen-1α-carboxylate ethyl ester (CPCCOEt) A: entrainment of bursting in bicuculline and strychnine is less effective in the presence of the mGluR1 antagonist CPCCOEt (50 μM) for both ventral (left, VR stimulation) and dorsal (right, DR stimulation) stimuli. The interval between the VR stimulus trains (5 stim at 20 Hz; only the last stimulus of the train is shown on the trace) was 7.5 s and between the DR stimuli was 5 s. The DR stimulus intensity was set just below the stimulus intensity to produce 100% entrainment, and resulted in some failures. B: CPCCOEt (50 μM) reversibly abolished locomotor-like activity evoked either by a train of ventral root stimuli (left, VR stimulation) or dorsal root stimuli (right, DR stimulation). Both stimulus trains were 4 Hz for 10 s and are shown by the bar (train stimulation) under the traces.