Table 4.
Odds Ratios (95% Confidence Intervals) for Dementia Associated with Macroscopic or Microscopic Infarcts Adjusted for Age, Sex, and the Presence, Number, or Location of Other Infarct Types
| Infarcts | Adjusted for Factors | ||||
|---|---|---|---|---|---|
| Sex, Age | Sex, Age, and Number of Deep Subcortical Macroscopic Infarcts | Sex, Age, and Number of Hemispheral Macroscopic Infarcts | Sex, Age, and Presence of Any Microscopic Hemispheral Infarct | Sex, Age, and Presence of Any Deep Subcortical Microscopic Infarct | |
| Macroscopic infarcts | |||||
| Number of total macroscopic infarcts | 2.0a(1.4–2.8) | 3.4a(1.7–6.7) | 1.2 (0.7–2.2) | 1.7a(1.1–2.7) | 1.9a(1.3–2.7) |
| Number of hemispheral macroscopic infarcts | 3.6a(1.9–7.1) | 3.4a(1.7–6.7) | 2.9a(1.4–6.0) | 3.3a(1.7–6.4) | |
| Number of deep subcortical macroscopic infarcts | 1.5 (0.9–2.5) | 1.2 (0.7–2.1) | 1.2 (0.6–2.2) | 1.4 (0.8–2.4) | |
| Any hemispheral macroscopic infarct | 5.6a(3.0–12) | 5.0a(2.0–12) | 3.5a(1.4–9.6) | 5.5a(2.2–13) | |
| Any deep subcortical macroscopic infarct | 2.0a(1.1–4.1) | 1.5 (0.7–3.3) | 1.5 (0.6–3.2) | 2.0a(1.0–4.1) | |
| Microscopic infarcts | |||||
| Any microscopic infarct | 9.3a(3.4–25) | 6.0a(2.1–17) | 1.3 (0.3–5.7) | 25a(3.0–200) | |
| Any hemispheral microscopic infarct | 40a(5–312) | 6.8a(2.2–21) | — | 37a(4.7–290) | |
| Any deep subcortical microscopic infarct | 3.8a(1.2–12) | 2.2 (0.6–7.8) 2.4 (0.7–8.2) |
1.5 (0.4–6.2) | – | |
The odds ratio refers to that associated with a single-step increase in the independent variable. Age refers to age at death.
a
Significant values, p < 0.05.