Table 2.

Poly(I: C) induces the secretion of cytokines, chemokines, and growth factors into the airways.

	Treatment
Protein (pg/ml)	PBS	100 μg Poly(I:C)
IFNγ	11.0 +/- 1.6	52.2 +/- 11.2 **
IL-1α	16.5 +/- 1.2	21.8 +/- 1.4 *
IL-6	8.8 +/- 1.5	879.0 +/- 171.2 **
CXCL10	30.3 +/- 5.9	411.3 +/- 34.9 **
JE	11.7 +/- 1.2	798.7 +/- 182.6 **
KC	6.2 +/- 1.3	55.4 +/- 6.5 **
GCSF	5.2 +/- 0.7	60.6 +/- 6.8 **
MIP1α	37.7 +/- 6.3	441.1 +/- 61.6 **
RANTES	0.5 +/- 0.04	155.8 +/- 41.6 **
TNFα	2.3 +/- 0.33	81.2 +/- 13.7 **
GMCSF	19.1 +/- 2.1	33.5 +/- 4.5 *

Mice were administered PBS or 100 μg polyI:C (I.N.) every 24 h for three days. 24 h following the last polyI:C administration, BALs were performed. Analyte levels in BAL were determined. Data are expressed as mean pg/ml ± SEM from 6 – 8 mice. Statistical significance was determined using the Mann-Whitney test. * p < 0.05, **p < 0.01 when compared to PBS-treated mice. There was no measureable change in the following cytokines (data not shown): IL-1β, IL-2, IL-4, IL-5, IL-7, IL-10, IL-12(p70), IL-9, IL-13, IL-15, or IL-17.