Table 1.
pO2 levels in the vitreous humor and lens center of various species.
pO2 (mm Hg) | ||||
---|---|---|---|---|
Cat | Rabbit | Guinea Pig | * Rat | |
A. Normal animals: | ||||
Close to the retina | 31 ± 3 (6) | 28 ± 10 (3) | 1.3 ± 1.1 (3) | |
Behind the lens | 6.8 ± 1.5 (6) | 4.0 ± 2.0 (3) | 1.3 ± 1.2 (3) | |
Lens center | 0.5 (1) | 2.0 ± 1.0 (3) | 0.6 ± 0.4 (5) | 5.6 ± 5.0 (6) |
B. Injected animals: | ||||
Lens center (MP) | 0.7 ± 0.4 (3) | **9.4 ± 4.0 (10) | ||
Lens center (HY) | 0.5 ± 0.4 (3) | 4.2 (2) |
A: pO2 levels are indicated for two locations in the vitreous humor and in the center of the lens for normal animals.
B: Lens center pO2 analyses were conducted 1–2 weeks after intravitreal injection of either microplasmin (MP) or hyaluronidase (HY).
Results are expressed as means ± S.D. with the number of analyses indicated in parentheses.
For comparison, we have previously reported that the pO2 level of normal rat mid-vitreous humor is 23mm Hg (Quiram et al., 2007).
p<0.05, compared to the lens center value for control rats shown in Table 1A.