Table 1.
Characteristics of patients treated by stereotactic reirradiation using single and multiple fractions and for local failures of nasopharyngeal carcinoma
| Stereotactic radiotherapy with single fraction (n = 43) |
Stereotactic radiotherapy with multiple fractions (n = 43) |
All (n = 86) |
|
| Gender | |||
| Male | 32 (74%) | 35 (81%) | 67 (78%) |
| Female | 11 (26%) | 8 (19%) | 19 (22%) |
| Age | |||
| ≤ 45 | 21 (49%) | 21 (49%) | 42 (49%) |
| > 45 | 22 (51%) | 22 (51%) | 44 (51%) |
| median (range)/years | 46 (32–84) | 46 (18–69) | 46 (18–84) |
| Type of failure | |||
| Persistent disease | 19 (44%) | 19 (44%) | 38 (44%) |
| Recurrent disease | 24 (56%) | 24 (56%) | 48 (56%) |
| Retreatment T stage | |||
| rT1 | 25 (58%) | 23 (54%) | 48 (56%) |
| rT2 | 5 (12%) | 7 (16%) | 12 (14%) |
| rT3 | 9 (21%) | 6 (14%) | 15 (17%) |
| rT4 | 4 (9%) | 7 (16%) | 11 (13%) |
| Time from 1st course of radiotherapy to reirradiation | |||
| ≤ 12 months | 23 (53%) | 24 (56%) | 47 (55%) |
| > 12 – 24 monhts | 3 (7%) | 8 (18%) | 11 (13%) |
| > 24 – 48 months | 6 (14%) | 6 (14%) | 12 (14%) |
| > 48 months | 11 (26%) | 5 (12%) | 16 (18%) |
| median (range)/months | 10 (3 – 197) | 10 (3 – 107) | 10 (3 – 197) |
| Tumor volume | |||
| ≤ 5 cc | 21 (49%) | 21 (49%) | 42 (49%) |
| > 5 – 10 cc | 13 (30%) | 13 (30%) | 26 (30%) |
| > 10 cc | 9 (21%) | 9 (21%) | 18 (21%) |
| median (range)/cc | 5.1 (1.3 – 30.7) | 5.6 (0.8 – 24.7) | 5.2 (0.8 – 30.7) |