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. 2009 May 23;1:13. doi: 10.1186/1758-3284-1-13

Table 2.

Subgroup analysis of treatment outcome after stereotactic radiosurgery or radiotherapy for local failures of nasopharyngeal carcinoma

3-year local failure-free rate 3-year overall survival rate
SRS SRM p value SRS SRM p value
Sex
 male 54% 87% 0.006 63% 63% 0.806
 female 42% 73% 0.275 75% 24% 0.067

Age
 ≤ 45 27% 87% 0.023 63% 44% 0.338
 > 45 49% 80% 0.028 67% 62% 0.702

Type of failure
 persistent disease 77% 94% 0.456 87% 90% 0.589
 recurrent disease 30% 75% 0.001 52% 35% 0.419

rT stage
 rT1 69% 88% 0.133 85% 79% 0.721
 rT2-4 28% 78% 0.006 45% 28% 0.458

Tumor volume
 ≤ 5 cc 62% 90% 0.219 79% 75% 0.502
 > 5 – 10 cc 61% 67% 0.342 78% 44% 0.117
 > 10 cc 69% 84% 0.106 25% 52% 0.108

SRS: stereotactic radiotherapy using single fracton

SRM: stereotactic radiotherapy using multiple fractions