Table 2.

Ezatiostat Hydrochloride Liposomes for Injection Treatment Administration

Phase 1
Doase Cohort (mg/m2)	# of Patients	Total # Cycles Administered	Median # of Cycles per Patient (Range)
50	6	16	3 (1–5)
100	3	10	4 (2–4)
200	3	19	7 (4–8)
400	7	36	8 (1–8)
600	7	32	5 (1–8)
TOTAL	26	113	4 (1 – 8)
Phase 2
Treatment (600 mg/m2)	# of Patients	Total # Cycles Administered	Median # of Cycles per Patient (Range)
Dose Schedule 1	10	93	8 (4 – 17)
Dose Schedule 2	18	117	4 (1 – 19)
TOTAL	28	210	7 (1 – 19)