TABLE 4.

Clinical characteristics of African Americans across ApoE and ApoC-I genotypes

	Without CAD			With CAD
African Americans apo ɛ4	H1/H1 (n = 23)	H1/H2, H2/H2 (n = 24)	P	H1/H1 (n = 17)	H1/H2, H2/H2 (n = 23)	P
Total cholesterol (mg/dl)	211 ± 39	180 ± 37	0.008	234 ± 65	209 ± 48b	NS
LDL-C (mg/dl)	141 ± 36	111 ± 35	0.006	158 ± 55	137 ± 48b	NS
HDL-C (mg/dl)	48 ± 10	49 ± 19	NS	49 ± 14	47 ± 18	NS
TG (mg/dl)	109 ± 43	100 ± 39	NS	134 ± 42	127 ± 69	NS
ApoA-I (mg/dl)	130 ± 23	123 ± 24	NS	132 ± 24	120 ± 28	NS
ApoB (mg/dl)	148 ± 39	122 ± 33	0.019	168 ± 52	144 ± 42	NS
Glucose (mg/dl)	112 ± 20	119 ± 54	NS	159 ± 96a	121 ± 47	NS
Insulin (μU/ml)	26 ± 47	20 ± 24	NS	31 ± 27	19 ± 18	NS
HOMA-IR	2.2 ± 1.4	2.7 ± 3.2	NS	3.9 ± 3.5a	2.5 ± 2.2	NS

Apo, apolipoprotein; CAD, coronary artery disease; HOMA-IR, homeostasis model assessment–insulin resistance. Data are means ± SD. P values were calculated using Student's t-test. Values for triglycerides, insulin and HOMA-IR were logarithmically transformed before analyses. Nontransformed values are shown.

^aP < 0.05 compared with H1/H1 across CAD status.

^bP < 0.05 compared with H1/H2, H2/H2 across CAD status.