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Schematic of age distribution of reticulocytes in bone marrow and reticulocytes and normocytes in the circulation under normal equilibrium conditions. Reticulocytes are produced at a rate 
in bone marrow. These are released into the circulation at a rate 
. All reticulocytes are released by age 
, and have a maturation time of 
hours. RBCs are randomly cleared at a rate 
and have a maximum lifespan of 
days. Not to scale.
