Table 1. Baseline characteristics of 2640 postmenopausal Swedish women diagnosed with breast cancer in 1993–1995, by body mass index.
BMI
|
||||
---|---|---|---|---|
<25 | 25–30 | >30 | P-value | |
No. of cases | 1267 | 997 | 376 | |
Mean | ||||
Age at diagnosis (years) | 62.4 | 64.0 | 64.7 | <0.0001 |
Parity | 1.8 | 1.9 | 1.8 | 0.34 |
Age at first birth (years) | 25.5 | 25.3 | 25.3 | 0.68 |
Age at menopausea (years) | 50.5 | 50.7 | 50.4 | 0.88 |
Current alcohol intake, g day−1 | 2.9 | 2.3 | 1.7 | <0.0001 |
Frequency (%) | ||||
High socioeconomic statusb | 54 | 47 | 39 | <0.0001 |
Ever HRT | ||||
Ever oestrogen alone | 14 | 10 | 7 | 0.0005 |
Ever oestrogen–progestin | 30 | 15 | 12 | <0.0001 |
Current smoker | 30 | 18 | 13 | <0.0001 |
Recent mammographyc | 65 | 60 | 64 | 0.64 |
Detection by screening | 57 | 63 | 65 | 0.012 |
Primary treatment | ||||
Surgery | 99 | 100 | 99 | 0.86 |
Chemotherapy | 8 | 9 | 11 | 0.15 |
Antioestrogenic therapy | 54 | 51 | 57 | 0.30 |
Radiotherapy | 64 | 62 | 63 | 0.96 |
Deceased at end of follow-up | 24 | 24 | 35 | 0.0003 |
Cause of death | ||||
Breast cancer | 15 | 15 | 21 | 0.0008 |
Other cause | 9 | 9 | 14 | 0.0014 |
BMI=body mass index (kg m−2); HRT=hormone replacement therapy.
P-value: two sided t-test for means and χ2-test for the frequencies comparing BMI >30 vs BMI <25.
Among women with a natural menopause.
High level includes medium- and high-level white collar workers.
Mammography within 2 years and 2 months before diagnosis.