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. 2009 Apr 14;100(9):1486–1491. doi: 10.1038/sj.bjc.6605025

Table 3. Breast cancer-specific mortality in relation to body mass index before diagnosis, by the use of HRT or by detection mode: the Swedish Breast Cancer Study 1993–2003.

  Breast cancer deaths/exposed Breast cancer mortality ratea HRb 95% CI HRc 95% CI
All women
BMI
  <25 162/1090 1.8 1.0 Ref. 1.0 Ref.
  25–30 126/873 1.7 1.0 0.8, 1.2 0.9 0.7, 1.2
  >30 66/322 2.6 1.4 1.1, 1.9 1.2 0.9, 1.6
             
Never hormone replacement therapy
BMI
  <25 108/628 2.1 1.0 Ref. 1.0 Ref.
  25–30 99/645 1.9 0.9 0.7, 1.2 0.8 0.6, 1.1
  >30 45/243 2.3 1.1 0.8, 1.6 0.9 0.6, 1.3
             
Ever oestrogen–progestin therapy
BMI
  <25 36/329 1.2 1.0 Ref. 1.0 Ref.
  25–30 10/130 0.9 0.8 0.4, 1.6 1.0 0.5, 2.1
  >30 13/40 4.3 3.7 1.9, 7.2 2.3 1.1, 5.2
             
Detected by mammographic screening
BMI
  <25 56/612 1.0 1.0 Ref. 1.0 Ref.
  25–30 52/548 1.1 1.0 0.7, 1.5 0.9 0.6, 1.4
  >30 29/209 1.7 1.5 0.9, 2.3 1.0 0.6, 1.6
             
Not detected by mammographic screening
BMI
  <25 104/466 2.8 1.0 Ref. 1.0 Ref.
  25–30 74/321 2.9 1.1 0.8, 1.5 0.9 0.7, 1.3
  >30 36/112 4.6 1.6 1.1, 2.4 1.4 0.9, 2.1

BMI=body mass index (kg m−2); CI=confidence interval; HR=hazard ratio; HRT=hormone replacement therapy.

a

Breast cancer deaths per 100 person-years.

b

Adjusted for age at diagnosis in 5-year categories, and current alcohol intake (0, 0–4.9, 5–9.9, and ⩾10 g day−1).

c

Adjusted for age at diagnosis, current alcohol intake (0, 0–4.9, 5–9.9, and ⩾10 g day−1), tumour size (⩽2, >2 cm), and lymph node positivity (no, yes).