Table 3. Correlation between CXCR4 expression and clinicopathologic factors in pancreatic adenocarcinoma.
|
CXCR4 expression
|
|||
|---|---|---|---|
| Variables | Low n=32 (%) | High n=39 (%) | P-value |
| Age, mean ±s.d. | 61.3±10.8 | 64.4±10.4 | 0.71 |
| Gender | |||
| Male | 16 (50) | 23 (59.0) | |
| Female | 16 (50) | 16 (41.0) | 0.48 |
| Tumour size | |||
| T1–T2 | 4 (12.5) | 6 (15.4) | |
| T3–T4 | 28 (87.5) | 33 (84.6) | 1.00 |
| Tumour differentiation | |||
| Well/moderate | 24 (87.5) | 32 (82.1) | |
| Poor | 8 (12.5) | 7 (17.9) | 0.56 |
| Lymph node | |||
| N0 | 16 (50.0) | 7 (17.9) | |
| N+ | 16 (50.0) | 32 (82.1) | 0.015 |
| Liver metastasis a | |||
| Present | 9 (28.1) | 23 (59.0) | |
| Absent | 23 (71.9) | 16 (41.0) | 0.016 |
| Vascular embols | |||
| Present | 9 (28.1) | 9 (76.9) | |
| Absent | 23 (71.9) | 30 (23.1) | 0.78 |
| Lymphatic embols | |||
| Present | 14 (43.8) | 25 (64.1) | |
| Absent | 18 (56.2) | 14 (35.9) | 0.09 |
| PI, mean±s.d. | 18.5±9.86 | 26.6±9.39 | 0.001 |
PI=proliferative index.
a
Recurrence during follow-up.