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. 2009 Jun;19(6):1124–1132. doi: 10.1101/gr.088013.108

Figure 1.

Figure 1.

Algorithmic overview of consensus calling for massively parallel resequencing. The program takes raw sequencing reads as input, maps them onto the reference genome, and calculates the likelihood of each possible genotype. It outputs the inferred genotype with highest posterior probability and its corresponding quality score.