Figure 3. AIP did not inhibit the epileptiform activity-induced increase in protrusion length.
Shown is a cumulative histogram plot of dendritic protrusion length. N indicates the total number of spines analyzed for each condition obtained from three individual experiments: GFP-expressing neurons maintained in control (GFPctrl) or Gbz-containing medium (GFPgbz) or GFP-AIP-expressing neurons maintained in Gbz containing medium (AIPgbz). There was a significant (χ2 test) difference in distribution between GFPctrl and GFPgbz (P < 0.001), and between GFPctrl and AIPgbz (P < 0.01). No significant difference was seen between GFPgbz and AIPgbz (P = 0.145).