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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: J Neurosci Res. 2009 Jul;87(9):1969–1979. doi: 10.1002/jnr.22033

Figure 5. Quantification of spines, filopodia and shaft PSDs under control and EA condition.

Figure 5

Hippocampal slice culture and transfection were done as described in Figure 3. A-C show distribution and mean density of (A) spines (dendritic protrusions that contain PSDs); (B) shaft PSDs; and (C) filopodia (dendritic protrusions that lack PSDs). Each diamond represents the density of PSD-95 clusters in one neuron. All neurons from three separate experiments were pooled together. N = 33 (Ctrl); 13 (AIP); 15 (Gbz); 13 (AIPgbz). (D) Total PSDs (shaft + spine). (E) All dendritic protrusions counted: spines (white) or filopodia (gray). (F) Filopodia:Spine ratio calculated from data in A-C. Significant differences are indicated by * P < 0.05 or ** P < 0.01 (Student's t-test).