Table 2.
Particles | Gene | Pathway | System | Author |
---|---|---|---|---|
MWCNTs | IL-10 IL-6 NQO1 |
Cytokine signaling Electrophile response |
Mice (C57BL/6) | Mitchell et al. [32] |
SWCNTs | AP1 NFk-B HLA-DR CD80 CD40 |
Redox-sensitive transcription factor Macrophage antigen-presenting function |
Mice (ICR) | Chou et al. [63] |
SWCNTs | NFk-B | Cell death and inflammatory response | Human keratinocytes (HaCaT) | Manna et al. [16] |
SWCNTs | p16* bax p57 hrk cdc42 cdc37 cdk2 cdk4 cdk6 cyclinD3 mad2 jak1 ttk pcdha9 erk p16* baxhrk bak1 p57 FGFR2 TGF beta receptor TNFAIP2 |
Cell cycle Signal transduction Apoptosis |
Human embryo kidney cells (HEK293) | Chui et al. [17] |
SWCNTs | HMO1 HMO2 ERCC4 TP53 Caspase8 ATM GADD45A |
Anti-oxidative, anti-inflammatory functions Protection from DNA damage Apoptosis Cell cycle Induced under genotoxic effect |
Human BJ Forskin cells | Sarkar et al. [69] |