Table 3.
Genes Affected by Nanomaterials Treatment
| Particles | Gene | Pathway | System | Author |
|---|---|---|---|---|
| PPI | IL-9 (gp96)-1 Cyclin h Cyclin a1 |
Inflammatory response Tumor rejection antigen Cell cycle |
Human epidermoid cell (A431) Human lung epithelial cells (A459) |
Omidi et al. [75] |
| Amorphous silica particles | IL-1β IL-6 IL-8 TNF-α MCP-1 MIP-2 |
Cytokine signaling Chemokine signaling |
A/J mice | Cho et al. [75] |
| TIO2 | B-cell receptor Death receptor NFk-B |
Immune response Apoptosis | BV2 microglia (immortalized mouse cell line) | Long et al. [89] |
| CoCl2 | Interferon-activate gene 203 RAB GTPase degenerative Spermatocyte homolog 1 |
Inflammatory response Secondary cellular response Involved in sintesis of fatty acids |
Mouse fibroblast (Balb/3T3) | Papis et al. [90] |