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. Author manuscript; available in PMC: 2009 Jun 9.
Published in final edited form as: Proteins. 2008 Jul;72(1):197–208. doi: 10.1002/prot.21908

Figure 3. Superposition of Homo sapiens FKBP1 with insect homologues.

Figure 3

Putative orthologues were superimposed in a pairwise fashion using the STRAP program to assess the degree of structural similarity among groups of FKBPs. FKBP1 from Homo sapiens (red) is superimposed with FKBPs from (A) Anopheles gambiae (yellow) and (B) Manduca sexta (green). Although FKBPs exist in all known organisms, their cellular roles have not been identified in a number of taxonomic groups. Structural similarity suggests that functional parallelisms may exist in a variety of organisms and the superpositions enable us to hypothesize about the utility of the FKBPs in species for which no function has been characterized.