Table 1.
PMCA and SERCA mRNA Expression Versus Treatment Time and H2O2 Concentration
| 4 hr, 10 µM | 8 hr, 10 µM | 16 hr, 10 µM | 4 hr, 10 µM | 4 hr, 100 µM | 4 hr, 200 µM | |
|---|---|---|---|---|---|---|
| PMCA1 mRNA | 1.8 ± 0.2 | 2.2 ± 0.3 | 3.3 ± 0.3 | 1.8 ± 0.3 | 2.4 ± 0.2 | 3.0 ± 0.3 |
| PMCA2 mRNA | 1.5 ± 0.2 | 2.0 ± 0.3 | 2.5 ± 0.2 | 1.6 ± 0.1 | 2.0 ± 0.2 | 2.9 ± 0.3 |
| PMCA3 mRNA | 1.1 ± 0.2 | 1.2 ± 0.2 | 1.2 ± 0.1 | 1.2 ± 0.2 | 1.2 ± 0.2 | 1.3 ± 0.3 |
| PMCA4 mRNA | 1.1 ± 0.2 | 1.1 ± 0.2 | 1.2 ± 0.2 | 1.1 ± 0.2 | 1.1 ± 0.2 | 1.2 ± 0.2 |
| SERCA2 mRNA | 1.5 ± 0.2 | 2.1 ± 0.2 | 2.9 ± 0.3 | 1.9 ± 0.2 | 2.4 ± 0.3 | 3.4 ± 0.3 |
| SERCA3 mRNA | 1.6 ± 0.3 | 2.0 ± 0.2 | 3.1 ± 0.3 | 1.8 ± 0.3 | 3.0 ± 0.3 | 3.4 ± 0.4 |
PMCA1 and 2 and SERCA 2 and 3 are statistically different, p < 0.05.
Data are average ± standard error of the mean, n=3-4.