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. Author manuscript; available in PMC: 2009 Jun 9.
Published in final edited form as: Sci Signal. 2008 Nov 25;1(47):ra15. doi: 10.1126/scisignal.1164263

Figure 6. LRP1 is involved in multiple signaling pathways.

Figure 6

A) RNA samples from wildtype and LRP1-deficient MEF were analyzed by Northern Blotting with cDNA probes for the genes indicated. Cyclophilin served as a loading control. A representative experiment of n=3 is shown.

Dkk-3 – dickkopf-3, C3 – complement factor 3, sfrp-1 – secreted frizzled-related protein-1, AHR – aryl hydrocarbon receptor.

B) RNA samples from wildtype and LRP1-deficient MEF and from LRP1-deficient fibroblasts stably re-transfected with an expression plasmid for LRP1 (control: empty plasmid vector) were examined for 25-cholesterol-hydroxylase expression. A representative experiment of n=3 is shown.