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. Author manuscript; available in PMC: 2009 Jun 9.
Published in final edited form as: Arch Neurol. 2008 Nov;65(11):1518–1526. doi: 10.1001/archneur.65.11.1518

Figure 1.

Figure 1

Multipoint logarithm of odds (LOD) scores for late-onset Alzheimer disease (LOAD). A, Multipoint LOD scores for a broad definition of LOAD (ie, definite, probable, and possible). Results for all 22 chromosomes are shown on a single graph. Single-nucleotide polymorphisms (SNPs) near the gene for apolipoprotein E (APOE) at 19q13.31−2 had the highest LOD scores. Additional SNP clusters at 7p22.1, 8p21.3, 6q21, and 18q12.2 also had LOD scores of 2.0 or greater in 1 of the analyses. B, Multipoint LOD scores for a narrow definition of LOAD (ie, definite and probable). Results for all 22 chromosomes are shown on a single graph.