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. 2009 May 19;5:269. doi: 10.1038/msb.2009.27

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Copyright © 2009, EMBO and Nature Publishing Group

This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits distribution and reproduction in any medium, provided the original author and source are credited. This licence does not permit commercial exploitation or the creation of derivative works without specific permission.

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Protein interaction network of PSD-95 interacting proteins. (A) 50 proteins of the PSD-95 core complex were connected, with 119 interactions segregated into 5 clusters (Cla–Cle) forming the MCC and two separate small clusters Clf and Clg. PSD-95/Dlg4 is showed in red, primary interactors of PSD-95/Dlg4 are shown in blue and secondary interactors are shown in yellow. The glutamate receptors (NMDA, AMPA and kainate receptors) and potassium channels are bracketed. (B) Schizophrenia susceptibility genes are shown in orange.