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. 2009 Apr 15;18(13):2431–2442. doi: 10.1093/hmg/ddp181

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© 2009 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — Gene ontology analysis performed on genes that are differentially expressed in cerebella and hypothalami of MECP2-Tg and Mecp2-null mice. Cellular component (A), molecular function (B) and biological process (C) categories that differ significantly between the genes activated by MeCP2 (yellow) and those repressed by MeCP2 (blue) are plotted. The standardized scores (Z-values) are presented on the x-axis, and significance was determined by a Z-value of more than ± 2 and a count of at least two genes. CNS, central nervous system; inflam., inflammatory; transmem., transmembrane.