Table 2.
Effect of sevoflurane anesthesia on serum chemistry values (mean± SEM) in KCG minipigs
| Before surgery | After surgery | |
| Total protein, g/dL | 7.9 ± 0.34 | 7.3 ± 0.05 |
| Albumin, g/dL | 4.4 ± 0.21 | 3.9 ± 0.11a |
| Albumin:globulin ratio | 1.3 ± 0.10 | 1.2 ± 0.05 |
| Total bilirubin, mg/dL | 0.13 ± 0.072 | 0.09 ± 0.009 |
| Direct bilirubin, mg/dL | 0.11 ± 0.055 | 0.08 ± 0.009 |
| Indirect bilirubin, mg/dL | 0.02 ± 0.018 | 0.01 ± 0.004 |
| Triglyceride, mg/dL | 24 ± 6.2 | 18 ± 3.7 |
| Phospholipid, mg/dL | 67 ± 7.3 | 57 ± 6.5 |
| Free fatty acid, μEq/L | 322 ± 73.5 | 234 ± 81.7 |
| Total cholesterol, mg/dL | 64 ± 2.2 | 63 ± 5.5 |
| Cholesterol ester, mg/dL | 49 ± 1.3 | 49 ± 4.4 |
| Free cholesterol, mg/dL | 15 ± 0.9 | 14 ± 1.1 |
| Cholesterol esterase, % | 77 ± 0.8 | 78 ± 0.5 |
| BUN, mg/dL | 16 ± 1.5 | 14 ± 2.3 |
| Creatinine, mg/dL | 1.09 ± 0.113 | 0.96 ± 0.124 |
| Sodium, mEq/L | 145 ± 1.9 | 139 ± 1.0 |
| Chloride, mEq/L | 103 ± 1.3 | 99 ± 1.2 |
| Potassium, mEq/L | 5.8 ± 0.45 | 4.0 ± 0.14a |
| Calcium, mg/dL | 10.2 ± 0.17 | 10.2 ± 0.27 |
| Phosphate, mg/dL | 7.6 ± 0.55 | 5.4 ± 0.24a |
| Asparatate aminotransferase, IU/L | 114 ± 61.3 | 59 ± 12.0 |
| Alanine aminotransferase, IU/L | 55 ± 6.3 | 39 ± 5.4 |
| Lactate dehydrogenase, IU/L | 630 ± 188.3 | 474 ± 42.3 |
| Alkaline phosphatase, IU/L | 485 ± 134.4 | 357 ± 128.2 |
| γ-Glutamyltransferase peptidase, IU/L | 60 ± 5.6 | 44 ± 3.0a |
| Cholinesterase, IU/L | 7 ± 0.7 | 4 ± 0.2a |
| Glucose, mg/dL | 70 ± 1.2 | 55 ± 4.5a |
a
Significantly (P < 0.05) different from preoperative value.