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. Author manuscript; available in PMC: 2009 Jun 9.
Published in final edited form as: Dev Biol. 2007 Mar 24;306(1):241–254. doi: 10.1016/j.ydbio.2007.03.024

Figure 8.

Figure 8

Activated SFKs associate with the nuclear envelope at the late pronuclear stage. Later pronuclear stage zygotes (24h post-hCG), 2-cell (48h) and 3- to 4-cell (60h) embryos were fixed and labeled with the clone-28 antibody as described for Figure 5. Activated SFKs were localized at or near the pronuclear envelope (Panel A, D). This peri-nuclear localization was still detectable at the 2-cell stage (Panel B, E). During mitosis (Panel C,F), activated SFKs were associated with the spindle (open arrow) and mid-body microtubules (closed arrow). Magnification is indicated by the bar which represents 10μm.