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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Mol Cancer Ther. 2009 Apr;8(4):959–970. doi: 10.1158/1535-7163.MCT-08-0905

Figure 1. Curcumin suppresses the proliferation of drug-resistant MM cells.

Figure 1

(A) Structure of curcumin. (B) U266 cells (5 × 103 cells) treated with various concentrations of curcumin, dexamethasone-sensitive (top-middle panel) and dexamethasone-resistant (top-right panel) MM.1 cells (5 × 103 cells), doxorubicin-sensitive (middle-left panel) and doxorubicin-resistant (middle-right panel) RPMI-8266 cells (5 × 103 cells), and melphalan-sensitive (bottom-right panel) and melphalan-resistant (bottom-right panel) RPMI-8266 cells were plated in triplicate, treated with 5 and 10 μM curcumin, and then subjected to MTT assay on days 2, 4, or 6 to analyze MM cell proliferation. Data are means ± SD for three experiments; **, P < 0.01; *, P < 0.05, vs. control.