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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Mol Cancer Ther. 2009 Apr;8(4):959–970. doi: 10.1158/1535-7163.MCT-08-0905

Figure 3. Curcumin suppresses the expression of antiapoptotic proteins in MM cells.

Figure 3

(A) Curcumin suppresses Akt activation in U266 cells. U266 cells (2 × 106/mL) were treated with 50 μM curcumin for the indicated times. Whole-cell extracts were prepared, separated on SDS-PAGE, and subjected to Western blot analysis using the indicated proteins. The same blots were stripped and reprobed with Akt antibody to show equal protein loading. (B) Curcumin inhibits the expression of antiapoptotic gene products. U266 cells (2 × 106/mL) were treated with 50 μM curcumin for the indicated times. Whole-cell extracts were prepared, separated on SDS-PAGE, and subjected to Western blot analysis using the indicated proteins. The same blots were stripped and reprobed with Akt and β-actin antibody to show equal protein loading.