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. Author manuscript; available in PMC: 2010 Mar 30.
Published in final edited form as: Virology. 2009 Jan 26;386(1):55–60. doi: 10.1016/j.virol.2008.12.026

Fig. 5. Mutation of rv-cyclin AD at Val260 affects the inhibition of NF-κB-dependent transcription.

Fig. 5

HeLa cells were co-transfected with a NF-κB-luciferase reporter vector (pNF-κB-luc), pFC or pFC-MEKK constructs, and control vector, pKH3 (white bars), or pKH3-rv-cyclin wild type (WT) or rv-cyclin AD mutations (V260F or V260S) (black bars). A Renilla expression vector with a thymidine kinase promoter (pRL-Tk) was also included. Results are reported as mean ± standard deviation of the ratio of luciferase activity versus Renilla activity from quadruplicate wells. The data presented in this figure are representative of two independent experiments.