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Schematic illustration of overview of one-carbon metabolism pathway, linking to methylation reactions and nucleotide synthesis. Hcy, homocysteine; SAM, S-adenosylmethionine; SAH, adenosylhomocysteine; THF, tetrahydrofolate; DHF, dihydrofolate; dUMP, deoxyuridine monophosphate and dUTP, deoxythymidine monophosphate.
