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. 2009 Jun 22;4(6):e5994. doi: 10.1371/journal.pone.0005994

Table 3. Suppression of CD4+CD25 cell proliferation by CD4+CD25high T cells expanded in the presence of RAPAa.

% suppression (mean±SD)
No RAPA 10±3
RAPA 1 nM 77±6
RAPA 50 nM 84±5
RAPA 100 nM 96±6
a

Suppression of autologous responder cell proliferation with cells of 6 normal donors. Treg and responder cells were obtained from PBMC and cultured±RAPA as described in Materials and Methods.