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. Author manuscript; available in PMC: 2009 Jun 11.
Published in final edited form as: Adv Drug Deliv Rev. 2008 Sep 20;60(15):1600–1614. doi: 10.1016/j.addr.2008.08.004

Fig. 5.

Fig. 5

Schematic presentation of the nanoparticle-based X-ray-induced PDT. Under ionizing radiation a nanoparticle starts to scintillate transferring its energy into a conjugated porphyrin molecule, which then generates singlet oxygen necessary to produce photosensitizing effect. This methodology will help to treat nodular and deeper tumours due to higher penetrating capacity of X-rays and gamma rays compared to that of visible light commonly used in PDT.