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. 2008 Oct 3;40(1):04. doi: 10.1051/vetres:2008042

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© INRA, EDP Sciences, 2008

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted use, distribution, and reproduction in any noncommercial medium, provided the original work is properly cited.

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Figure 4. — Photomicrographs displaying granularly stained PrP^TSE detected by immunohistochemical labeling (A, C, D) or PET blotting (B) at 30 or 45 dpi in the GALT of hamsters fed with 263K scrapie brain homogenate. PrP^TSE appears as brown (A, C, D) or blue-magenta (B) granular material. (A) Ileal lymphoid follicle at 45 dpi showing PrP^TSE in the germinal centre (arrowhead and inset in A). (B) PET blot in adjacent section to the specimen displayed in A (PrP^TSE is indicated by arrow). (C) Higher magnification of inset in A. (D) Detection of PrP^TSE in the germinal center of an ileal lymphoid follicle at 30 dpi. Scale bars in A and B, 40 μm; in C and D, 5 μm. (For a colour version of this figure, please consult www.vetres.org.)